An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.

Erica Shepherd is a brilliant former CIA operative, now known as the most notorious traitor in American history serving life in a Supermax prison. Against every fiber of his being but with nowhere else to turn, FBI Agent Will Keaton enlists Shepherd to help track down a fiercely dangerous and elusive criminal she knows all too well. While Shepherd and Keaton have different motivations for bringing the enemy to justice, they both know that to catch a spy… they must think like one.

Set in downtown New York in 1900, 'The Knick' is centered on the Knickerbocker Hospital and its staff, notably Dr. John Thackery, the hospital's brilliant chief surgeon who pushes medicine's boundaries, pioneering new procedures despite a severe drug addiction.

Set during the Cold War period in the 1980s, The Americans is the story of Elizabeth and Philip Jennings, two Soviet KGB officers posing as an American married couple in the suburbs of Washington D.C. and their neighbor, Stan Beeman, an FBI Counterintelligence agent.