When the entire world blacks out for two minutes and seventeen seconds, everyone sees a flash of their own future 6 months from the present. For some, the future is hopeful, while for others, it is unexpected. For a few, it doesn't seem to exist. Knowing their fate will alter each person's life, destinies will be changed.

Dr. Gregory House, a drug-addicted, unconventional, misanthropic medical genius, leads a team of diagnosticians at the fictional Princeton–Plainsboro Teaching Hospital in New Jersey.

A family comedy narrated by Katie, a strong-willed mother, raising her flawed family in a wealthy town filled with perfect wives and their perfect offspring.