The space police force known as the "Jetters" fight against the villains making sure that the universe is safe.

The future of dueling is revving up! And with it begins a new legend! Yu-Gi-Oh! 5D's! Welcome to New Domino City! Once the playground to legendary duelist Yugi Muto, this sprawling metropolis has since been transformed into a futuristic society where dueling has kicked into overdrive. With recent technological advancements made by KaibaCorp, dueling has undergone a metamorphosis that has revolutionized the makeup and pace of the game! It’s now a heart-pounding, adrenaline-filled and fuel injected competition where duelists ride supercharged hyper cycles called Duel Runners and battle it out in hi-octane contests called “Turbo Duels.” The winners and losers aren’t just separated by skill and strength… but by SPEED! However, for five special duelists, it's not just about winning or losing anymore - it's about survival, for they are the chosen "Signers" who have been marked by destiny to uncover the secrets of the five dragons!

Gaimetal, a metallic mineral with high amounts of pure energy, was discovered 50,000 meters underground in 2047, and began mining worldwide. However, Gaist, which are metallic life forms whose bodies are fully embedded with Gaimetal emerged in 2055 and started to attack people. In 2064, Rekka, Hayato, Kurama, and Siren are among those known as Gear Gaist and they faced the battle with more than 100 varieties of creatures Gaist.

Natsume Takashi has the ability to see spirits, which he has long kept secret. However, once he inherits a strange book that belonged to his deceased grandmother, Reiko, he discovers the reason why spirits surround him.

A princess from the Land of Jewels comes to Earth with the Kirama Stones to find individuals with strong "shining spirits" known as Kiramental to become the Kiramagers and fight the threat of the Yodon, an imperial army of darkness.