General Rouge no Gaisen is a 12-episode Japanese medical drama television series broadcast in 2010, a sequel to the series Team Batista no Eikō. Atsushi Itō and Tōru Nakamura reprised their lead roles. The initial season of "Team Batista" aired on Fuji TV in late 2008 and pulled in strong ratings, leading to a follow-up last October in the special episode "Nightingale no Chinmoku." The dramas were based on the first two novels in a best-selling medical mystery series by writer Takeru Kaido. The new season is based on the third novel, General Rouge no Gaisen. Both "Team Batista no Eiko" and "General Rouge no Gaisen" have also been adapted as a feature films, starring Yuko Takeuchi and Hiroshi Abe. Fuji TV will broadcast "Team Batista 2: General Rouge no Gaisen" on Tuesdays at 10:00pm, beginning on April 6. New cast members this time include Hidetoshi Nishijima, Ai Kato and Miho Shiraishi.

Akari works as a manager at a cafe. She is sincere and she has a good reputation with those around her, but she has a secret. Due to a video, Akari gets popular on social media. Soon, her family, who have peaceful lives, get involved in the social media world.

Rookie police officer Chinami (Emi Takei) is assigned to work on the investigation team. On her first day, she is designated for assignment. Chinami is teamed up with a handsome detective. They work together to solve difficult cases, while Chinami often gets scolded by the veteran detectives.

Superintendent Kobayakawa Fuyuhiko is a naive career police officer who cannot read situations. He is transferred from the Tokyo Metropolitan Police Department’s National Research Institute of Police Science to the newly established “anything” consultation office of Suginami Chuo Police Precinct’s Community Safety Division as a result of some incident.

Centered around typical Japanese food, a solitary salesman travelling through the country for business purposes, eats at its various establishments and experiences the various delicacies of Japanese cuisine.

One night, Manda Ginjiro a moneylender in the Minami district of Osaka, hears a gunshot echoing in an alleyway. The shooter is Yojiro Todoroki , one of Ginjiro's clients. Todoroki entrusts Ginjiro with his notebook, which he has been holding onto with great care, and runs out of steam. From that day on, a suspicious shadow begins to haunt Ginjiro. According to Hideo Sawaki, a bigwig in Minami, an organization is trying to kill Ginjiro.

Daimon Michiko is a 37-year-old freelance surgeon who is part of a questionable “doctor placement service” that has her wander from hospital to hospital. The harsh environment at the hospitals led many doctors to retire from their positions, forcing hospitals to make use of said program to fill the empty spots at least temporary. However, Michiko doesn’t look like a doctor at all with her flashy clothes and eccentric attitude. In the first episode she raises objections to a certain operation which is planned to be done by the head of a hospital who hasn’t performed an operation for a very long time. This causes Michiko to incur odium at the hospital, however, everyone becomes frozen when Michiko points out the outdated skills of the director. She also holds a scrupulous compliance when it comes to her working hours, never does any unnecessary chores that don’t require a medical license, and couldn’t care less about the power struggles within the hospitals. Nobody knows how she acquired such a top-level skill that allows her to claim exorbitant sums as reward, but her private life is an even greater mystery to everyone around her. Tanaka plays a rookie surgeon, Uchida an anesthetist, Kishibe the head of the placement service, and Ito the head of the surgical department of this institution.

After participating to a previous show where they have to bet or be challenged to any kind of competitions, the losing members of the Gaki no Tsukai are selected to spend 24 hours in a setting which they have no knowledge of the theme nor the course of the events. They are exposed to various absurd and crazy situations nonstop for 24 hours and must refrain from laughing. If they do so, hang-men appear and hit the rule breakers with a weapon (the weapon varies every year).

Produced by Hitoshi Matsumoto, Documental pits ten comedians against each other. The objective is to make each other laugh in a closed room. Each contestant brings a one million yen participation fee. The last person to stay in the room without laughing wins. The winner is awarded a 10 million yen prize and bragging rights as the funniest comedian.

University student Wakamizu Ryota (Emoto Tokio), who is the middle of job hunting, gets caught up in a sudden gang dispute. Ryota’s life is saved by Yanagiba Ryuichi (Namase Katsuhisa), the boss of Yanagiba-gumi, and Ryota for some reason ends up harbouring Yanagiba in his own home. Ignoring Ryota who wants him to leave immediately, Yanagiba uses the leftover food in the fridge and starts to prepare a meal without asking. However, the meal is surprisingly delicious despite the leftovers that did not seem possible to combine. This is the beginning of a bizarre communal life connected by meals for a gangster and a university student.

There exists a legendary team of surgical experts in Tojo University Hospital that specializes in the Batista procedure - one of the most difficult cardiac surgeries with the survival rate only at 60%. Ever since its formation, this team has shocked the country by having 27 consecutive post-operative successes, virtually unheard of in the medical community. They basked in the glory until three of the most recent procedures resulted in consecutive deaths on the operating table. Taguchi, a psychosomatic medicine specialist, has been entrusted with the investigation but is in over his head because of his soft nature and having to deal with skills beyond his realm of expertise. Then arrives Shiratori, a cocky Ministry of Health Labor and Welfare investigator. He not only labels Taguchi naive, but speaks with confidence that this is a murder, and the murderer is within this team of elites. As the mystery unfolds, so does the complicated affiliation between each of the seven team members.