Arcadia is plagued with evil, life-draining demons called Thanatos and a vast lack of Purifiers to exterminate them all. While attending school, Angelique attracts the eye of a man who intends to turn the tides to the people's favor. What lies within her is the key to Arcadia's survival.

The Sakuragoaka Girls' Academy curriculum traditionally focuses on the three "R"s of reading, writing and arithmetic, but Ritsu Tainaka wants to add two more "R"s: Rock and Roll! To do that, however, Ritsu has to save the Light Music Club from being shut down due to little problems like not having any other members or a faculty advisor. After strong-arming her best friend Mio into joining and convincing Tsumugi Kotobuki to make it a trio, Ritsu's would-be rockers are soon only one talented guitarist short of the quartet they need for school approval. What they get, unfortunately, is Yui Hirasawa, who's never held a guitar in her life, but she's determined to learn! Will the school halls come alive with the sound of music?

Takeshi Hongo is a promising young man with a passion for motorcycle racing. However, his dreams are suddenly ruined when he gets kidnapped by Shocker, the evil secret organization planning to dominate the world. After being remodeled into a cyborg, Takeshi escapes and swears to protect the world from the inhuman monsters.