After a tarot reader tells her that the love of her life is not in the future, but in the past, and that she must find him before her 30th birthday, young and impulsive María undertakes a desperate search to find love, with the help of her best friends: Pedro, Ana and Lolo, and thus create her list of exes.

Victoria is a free spirited girl from a humble background and an aspirant Sprinter. She was abandoned by her biological mother when she was a child. A woman named Chencha took her in and treated her as her own daughter. Victoria dreams to become a Champion at the Olympics and much determined to fight any obstacle that gets her way. Victoria also finds herself in between two men, Andres and Raul who are willing to fight for her love.

Rebeca murders her sister Adriana to end up with the man she loved, and becomes the step mother of her niece Lucía. Nora, Lucía's half sister and daughter of Rebeca, resents Lucía for the same reasons Rebeca hated Adriana, as history repeats itself.

La vecina, is a comedy-telenovela produced by Lucero Suárez for Televisa. It is the remake of the telenovela La costeña y el cachaco produced in 2003 by RCN TV.