Three women become entangled in the world of human trafficking and prostitution when Esther's husband suddenly disappears. From completely different worlds, the lives of these women become intertwined. They discover that they need each other to escape from the difficult situations they find themselves in.

This series takes place at a cutting-edge city hospital. The first season follows Ella, a skilled obstetrician who leads a team of fellow medical professionals. Together, they must perform under immense pressure. The healthcare providers and their patients represent all walks of life and amidst their many triumphs and struggles, laughter and tears occur in equal measure. The thin line between one's personal life and one's professional life becomes increasingly blurred when working such long hours, making conflict unavoidable. But in the end, there is one thing that unites everyone on this parallel hospital-universe: the universal human experience of new life, fragile yet filled with hope and potential.

Carmen, the daughter of a notorious Amsterdam drug lord, reluctantly takes charge of the family's smuggling business in order to clear her husband's debts.

Astrid Holleeder works towards the moment when she definitively betrays her brother to Justice. Flashbacks make it clear what childhood she and her brother have wrestled themselves with and how painful, but necessary, her betrayal is.