During the Edo period of Japan, out of the fear of losing authority, the Tokugawa shogunate hires the Shinsengumi to bring down the Imperial Court. However, the Satsuma Clan finds out about the Tokugawa's scheme and sends the last five Kunoichi (female ninjas) of Hiryu Ninja Clan, to spy on the Shinsengumi. Meanwhile, an evil skeletal demon is brought to life to murder the Kunoichi ninjas and destroy the world.

A history club member commits suicide by jumping off the school building. Hazuki is curious about the mysterious message, so she consults her father, a detective. She infiltrates the club and begins investigating her. The granddaughter of the powerful Hatsune holds the key to the incident. Hazuki is whipped by Hatsune and lured out by her homeroom teacher, Junko, who indulges in her pleasure. Hazuki is then raped and abducted by Hatsune's men. Hazuki had begun to touch the core, but the tragedy and humiliation had only just begun.

Nami Matsushima, a former doctor, is put in prison for murdering one of the men who raped and killed her sister. Now, faced with violent and lecherous prison gangs, an aggressively amorous warden, and with a friend on death row, Nami must steel herself for a ten year stay in one of Japan's toughest women's prisons.