The series follows the story of three siblings of a sick parent: two obsessive daughters – Safiye and Gülben and one son – Han, who has devoted his whole life to catering to his family's needs, shuttling tirelessly between work and home. One faithful day, Han's world will change as soon as he sees and immediately falls in love with İnci. For the first time in his life, Han will seek out his own happiness.

Eylul the stubborn, school girl turns up to be a strong professional doctor by the help of her teacher Ali Asaf. After years of separation they meet up again but not as a teacher and student, instead as surgeons working side by side. Their love is met by many challenges and the inner conflict of the stubborn women who refuse to yield easily to her heart, refusing to repeat the miserable story of her dead mother.

Bulut is working for Ferman Köklükaya, the owner of a big construction company. A successful and ambitious man, Bulut is also married to Ferman's spoiled daughter Sude. Ferman caused the death of Bulut's father working as the site manager; but Bulut does not know about this yet. Sude and Bulut have an unhappy marriage and one day, at a hotel opening, Bulut meets the young and beautiful promising violinist Melek. It is love at first sight.

The story of the efforts of six siblings, Azize, Cemo, Zeliha, Fidan, Samet and Balım, who lost their parents suddenly and in one night, to stay together and hold on to life despite the disasters that befell them. Although the story takes place in Istanbul, the tragedy that befell the siblings lies in the great love of their parents, Bala and Rıfat. This impossible love begins far from Istanbul, in a village in Mardin.