Maquia is a member of a special race called the Iorph who can live for hundreds of years. However, Maquia has always felt lonely despite being surrounded by her people, as she was orphaned from a young age. She daydreams about the outside world, but dares not travel from her home due to the warnings of the clan's chief. One day the kingdom of Mezarte invades her homeland. They already have what is left of the giant dragons, the Renato, under their control, and now their king wishes to add the immortality to his bloodline. They ravage the Iorph homeland and kill most of its inhabitants. Caught in the midst of the attack, Maquia is carried off by one of the Renato. It soon dies, and she is left deserted in a forest, now truly alone save for the cries of a single baby off in the distance. Maquia finds the baby in a destroyed village and decides to raise him as her own, naming him Ariel. Although she knows nothing of the human world, how to raise a child that ages much faster than her.

Set in the continent of Babel, where the Tower of Babel looms large over seven nations. After the invention of alchemy led to its use as a tool of war that brought humanity to the brink of extinction, the seven nations struck an uneasy peace that led to a prohibition on alchemy for hundreds of years since. In the Continental Year 911, the nation of Lustrice broke the pact by assembling an army bolstered by alchemy, with ambitions of conquest over the continent. Led by Envylia, the six nations allied and struck down the rogue nation, casting alchemy once again to darkness. But 20 years after the war, alchemy once again begins to cause chaos in the land.

Kyoko, who couldn't believe anything in the world and lived a desolate life, meets Katsuya Honda, who has been assigned as an educational trainee. She is at the mercy of Katsuya, who is rude and has a strong habit, and she is gradually attracted to her. However, she is disowned by her parents in the wake of an incident with her bad fellow. It's a punishment that I've been doing as much as I like. Katsuya appears in front of Kyoko who thinks so...

Fūka, a little witch, is training to be a better witch like her mother, a queen of Silver Castle. She is a lively girl and cares about her friends, but she gets into trouble sometimes. Karin, a princess of Green Castle, is Fūka's best friend; and Chitose, a prince of Blue Castle, is her friend from childhood.