The Great Ak calls a council of the Immortals to ask that Santa Claus be given immortality. And to justify it, he tells the history of Santa Claus. The Ak found an abandoned baby and gave it to a lioness and a fairy to raise, who named him Claus. When Claus grew up, the Great Ak showed him the evil and hardship in the world and Claus decides to live there and relieve some of the suffering. He decides to make toys for orphans, but King Awgwa, the ruler of the valley where Claus lives doesn't want the children to be happy, and there is a great battle among Immortals.

Lion-O is haunted by nightmares of Thunderians being killed on Thundera while he fled to the safety of Third Earth with Jaga and the other ThunderCats. Jaga later tells Lion-O that three more Thunderians have, in fact, survived and are also living on Third Earth. The ThunderCats decide to search for the other Thunderians, but Mumm-Ra has plans as well and takes the new Thunderians as his prisoners to Fire Rock Mountain. Lion-O loses the Sword of Omens in an avalanche while Panthro battles the Fist-Pounder with the ThunderTank as the ThunderCats close in on rescuing the Thunderians from Fire Rock Mountain, but they'll need supernatural help if they are to pass through the Thundranium gasses to reach them...

In New York City, a relationship is threatened when a young man discovers he's caught syphilis from a tryst with a waitress named Ellie. This threatens his relationship with a new girl. Film critic Amy Taubin co-stars as the new girl who gets the bad news. The director is apparently the same man who edited Fritz Lang's The Testament of Dr. Mabuse.

In this sex farce, two middle-aged pairs of aspiring swingers rent a summer cottage. There they sit around discussing the pros and cons of having affairs.

The major sub-plot circles around the youngest Griffin, Stewie, who has a near-death experience at a pool when a lifeguard chair falls on him, but he survives. After having a vision of being in Hell, he decides to change his ways, but this doesn't last long. While watching television, he and Brian spot a man that looks like Stewie. Brian is convinced that he is Stewie's real father, until Stewie learns that the man is actually himself as an adult, taking a vacation from his own time period. Baby Stewie visits thirty years later to discover that his adult self, going by the name Stu, is a single blue-collar middle-aged virgin working at a Circuit City-type store. Meanwhile, Peter and Lois are trying to teach their two older kids, Meg and Chris, to date. In the future, Chris, who hasn't changed much, is working as a cop and is married to a foul-mouthed hustler named Vanessa. Meg is now called Ron, since she had a sex-change after college.

A dog tries to become a canine star with the help of Zsa Zsa Gabor.

Earthlings chafe at the peace established by a benevolent alien race and set about to rebel.

A presumed-dead man's current wife and former wives squabble over his funeral arrangements.

From beyond any known galaxy, bringing with them the laws and ideas of their doomed planet, come the ThunderCats. These brave and courageous cat-like humanoids carry with them the powerful Sword of Omens, which contains the mysterious Eye of Thundera- the source of the power of all ThunderCats. But there's also a treacherous band of hideous mutants from the planet Plun-Darr who want the sword. Crash landing on Earth, the ThunderCats battle these evil creatures who are aided by the supernatural powers of the deadly and mysterious Mumm-Ra. You'll experience many incredible adventures in this epic science fiction saga.