Well-intentioned Marsha and David hire a foreign housekeeper, Sophia, to care for their new baby and put some 'sanity' back in their lives. What follows is a situation that spirals out of control. In a frenzy to find an American husband before her visa expires, Sophia manipulates poor Marsha and David into caring for her ten-year-old daughter while she goes on a dating marathon. Pretty soon, who is employing whom, becomes the question. Also thrown into the mix are Marsha's hypochondriac father, Sophia's eccentric Mama and cousin Sasha from the Moscow circus.

For Tammy, a burger-joint employee, a bad day keeps getting worse. She wrecks her car, loses her job and finds that her husband has been unfaithful. It's time for Tammy to hit the road, but without money or transportation, her options are limited. Her only choice is a road trip with her hard-drinking grandmother, Pearl, who has a car, cash and an itch to see Niagara Falls. It's not the escape Tammy had in mind, but it may be what she needs.

After Dick Harper loses his job at Globodyne in an Enron-esque collapse, he and his wife, Jane, turn to crime in order to handle the massive debt they now face. Two intelligent people, Dick and Jane actually get pretty good at robbing people and even enjoy it -- but they have second thoughts when they're reminded that crime can hurt innocent people. When the couple hears that Globodyne boss Jack McCallister actually swindled the company, they plot revenge.

Acclaimed therapist Dr. Mark Lembeck (Jason Alexander), having suffered a "psychotic fracture", attempts to restore his reputation by offering free sessions out of a community rec center.

A titan of industry is sent to prison after she's caught for insider trading. When she emerges ready to rebrand herself as America's latest sweetheart, not everyone she screwed over is so quick to forgive and forget.

After one short blind date, Mary Horowitz, a brilliant and eccentric crossword constructor, is convinced that Steve, a CCN cameraman, is her soul mate. Because his job takes him hither and yon, she crisscrosses the country following Steve, with the encouragement of a reporter, turning up at media events he's at to convince him they are perfect for each other. Along the way, she befriends an assortment of misfits who accept her for who she is, leading her to reassess her reasons for this strange journey.

Junior congressman Evan Baxter, whose wish is to "change the world" is heard by none other than God. When God appears with the perplexing request to build an ark, Evan is sure he is losing it.