Many lawyers consider themselves prophets, but Eli Stone may be the real deal. Eli has built a successful career at a top law firm in San Francisco representing only the biggest and richest corporations that make a habit of screwing over the little guy. But after experiencing a series of odd hallucinations, Eli seeks to find a deeper meaning to life while trying not to lose his job and destroy his relationship with the bosses' daughter. When Eli discovers an aneurysm in his brain, he wonders if his condition is truly medical or if perhaps he now has a higher calling.

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes.

Amy and her friends at Grant High learn to define themselves while they navigate the perilous waters of contemporary adolescence. Between their love triangles, secrets, drama, accusations, gossip, confusion, and scandalous rumors, there's never a dull moment.