A humble office worker's peaceful family life comes to an end after he makes a grave decision for the sake of his family.

In Osaka, Sayoko Takeuchi indulges in her evil ways. She targets old wealthy men and marries them for future inheritances. She works with Toru Kashiwagi who runs a marriage agency. Sayoko Takeuchi is married to a wealthy elderly man. One day, Tomomi Nakase hears her father was taken to the hospital. She rushes to the hospital and learns her father is unconscious. She also hears for the first time that her father is married to Sayoko Takeuchi. Tomomi Nakase takes the first steps in stopping Sayoko Takeuchi from gaining her father's fortune. She hires private detective Yoshinori Honda to investigate Sayoko Takeuchi and Toru Kashiwagi.

Yohei Ueshima is a so-called "Hikikomori Survivor", who had been isolated for 11 years since he was 38. He finally escaped from his room three years ago. After the escape, he opened a yakitori restaurant with the help of the local residents, but he could not talk to customers properly and was still in the process of reintegrating into the society. One day he was hired as a part-time teacher at a municipal junior high school. While struggling with various problems around him, he receives support from his withdrawal friends and supporters.

Born in an affluent family, Sakurako is grown beautiful but rather spirited and speaks roughly. As an osteologist, she reconstructs skeletal remains of animals in her atelier at home when receiving job offers from museums. Deeply inspired by the beauty and majesty of bodies, her eccentricity is remarkable. "Dead bodies speak eloquently." says Sakurako, at the events of examining incidents. She observes bodies and the crime scenes very carefully, and reveals the truth one by one. Kujo Sakurako, the beautiful osteologist, resolves the cases with her expertise hearing the "voice" of bones. How does this extraordinary heroine resolve cases?