A romantic comedy set during the reign of Rama 5 (Chulalongkorn). Thong In is an experienced doctor who has treated many people. He has a grandson named Thong Ake who wants to become a traditional doctor. He also studies ancient Thai medicine. One day, Thong In isolates himself after one of his patients dies and he's blamed for his death. He doesn't want Thong Ake to become a doctor and go through the same. Still, Thong Ake is determined to prove himself to his grandfather.

Bua, a medical student from today’s 5G era, is mysteriously swept back to King Rama III's reign – the golden era of Thai traditional medicine. Immediately thrown into an unknown world where she finds allies and rivals, her modern ways inevitably clash with old traditions.

Pong Lang dancing is Plengpin's favorite thing, but her mother who's a former top Pong Lang dancer always tries to stop her from doing it. Daopradub is planning to make the Pong Lang group of E-Sarn Orn Sorn come back with a new generation of dancers. She's impressed by Plengpin's performance and offers her a chance to audition for the group. Poom, Duenpradub's son, convinces her parents to let her join after she helps him get away from ruffians. Plengpin's intention is not only to pursue her dream but also find out what happened in the past. Why are her parents against her being a Pong Lang dancer?

She is spicy, saucy, and gutsy. She will get you every time! Lukkaew is petite in size but big on character and can be feisty. Her nickname is Little Miss Sassy (Gaenkaew!) She is an advocate for sustainable farming. She has been pushing several farmers to move towards a farming system that is more sustainable – environmentally, economically, and socially. It is not an easy task, and she has an uphill battle to tackle because she is young and the farmers don’t quite understand the system. To make matters worse, she comes across Saran, the new Forest Chief who always goes by the book, and refuses to go by her rules. She has to deal with the farmers and Saran, who is her no. 1 enemy. The battle of wit and sauciness is about to begin!

A young police officer named Akkanee who goes in search for the people who brutally murdered his troubled twin brother to whom he has not seen in 8 years. His search takes him to a world of lawlessness within a network of yaba (meth)t manufacturing and smuggling in rural Thailand. There is two rivaling farms in this lakorn, one owned by nang’ek’s grandfather and another owned by a yaba drug lord who manufactures yaba at his property.