Secluded mountain village in northern Fujian is in a state of panic. On the wedding day of Dong Wenhui and Qian Xiuchen father of the groom was tragically swallowed by a python. When Dong Wenlin threw the snake corpse on the altar, the python king swore to revenge. The story of the movie originated from the primitive snake culture in northern Fujian. According to legend, since the Qin and Han dynasties, the ancestors believed in snakes as the god of ancestors and worshiped them as totems. They do not fight snakes or eat snake meat. . This custom has been preserved to this day, and many ancient myths have also been derived. Among them, the legend of "The Long Snake Immortal Marries His Wife" is the most popular, and "Mutated Python" is based on this adaptation.

"Jian" is the number one killer in the Qisha Villa. As he decides to silently quit, his assassination is ordered by the Villa owner. He was lucky to have been saved by Xu Yi Yi, and in the new warm home, he has a new-found determination to live on.

Covert security company Vanguard is the last hope of survival for an accountant after he is targeted by the world's deadliest mercenary organization.

The film follows a cab driver who must endure a number of awkward passengers as he attempts to earn a living during a single night.

Racer Lin Chuang admired his rival Liang Zi, a pungent and hearty beauty, and followed her in the desert off-road race. At night on the track, the supply station where everyone rested was attacked by a mysterious monster at night. After Lin Chuang and his companions escaped by chance, they determined to retrieve Liang Zi who had driven away alone. A group of people chased to an abandoned factory nearby and found that the wealthy businessman Xiong Kun and his men were exploring rare minerals here. The two forces gathered in the desert forbidden area and started a death expedition. The frenzied attack by unidentified creatures officially kicked off. The two teams suffered heavy casualties and were trapped in the factory. Finally, it was discovered that the giant monster that revealed its true face under the dust was the sand python that failed to be transformed by the underground laboratory.

Zhang Yingchuan, a descendant of the Faqiu clan, took his niece Ono to live in seclusion after an accident when he was visiting the grave to find medicine.

Taxi driver Dong Dabao occasionally gets an ancestral antique washbasin. With unusual gift comes more temptations and tests. After a series of farce of losing and regaining Dong Dabao also gains something more important than wealth.

After his fiancé sudden death, Qin Yu is convinced Cass Corporation is somehow involved and is determined to find the truth. Booking passage on the same cruise ship as former Cass employee, Jason, Qin Yu follows him. Qin Yu hopes to secure the information he needs on Cass to be able to testify against them in court. But Qin Yu isn’t the only person on board hoping to gain intel on Cass. Desperate for a story, reporter Feng Li tails both Qin Yu and Jason, booking passage on the same cruise. Unfortunately, no one has much of a chance to gain information as the ship is suddenly attacked by giant mutant snakes. Escaping the attack, the survivors find themselves on the very island Cass Corporation has been conducting their illegal experiments. Hunted by monsters of all sorts, will any of the survivors find a way to bring Cass down and make it off the island alive?