Carlão is a taxi driver who experiences a drama of conscience after fleeing bank robbers leave a suitcase with stolen money in his car: he doesn't know whether to hand it over to the police, running the risk of being accused of being an accomplice in the robbery, or whether to use the money to solve his problems.

In the tiny poor town of Asa Branca, in the middle of Brazilian Northeast, Roque Santeiro is worshiped as a saint. He was supposedly killed by a bandit, 18 years ago, trying to save the local church. After his disappearance, local leaderships such as landowner Sinhozinho Malta and mayor Florindo, took profit on that to control the humble population. They even make up a widow, Porcina, who should have married Roque secretly before his death. What they don't expect is that Roque is alive, and he's back to, allegedly, "save his people". Now Malta, Florindo, Porcina, and others must hold him down and explain the "truth" to their commoners, in a desperate attempt to save their own bottoms. Meanwhile, mysterious facts surround Asa Branca, such as a Werewolf, a film crew who are trying to shoot a movie about Roque's story, and violent murderers.

The story follows the experiences of Marina, a young country bumpkin who marries the mysterious and charismatic widower Roberto Stein, a fabulously wealthy businessman living in 1920s Rio de Janeiro. As Marina attempts to acclimate to her new marriage and responsibilities, she discovers that Stein's late wife, Alice, still seems to have a strong hold over the household. Despite her new husband's affection for her, Marina is nonetheless threatened by Alice's presence, which is made conspicuous through her old maid Juliana's obsessions and her intimidating portrait.