Iwata Koichi and Kagawa Midori are second-year students at Tozaiyama High School. One day, while coming home from school, they discover a shooting star rising up in the sky. The next day, Midori sees a shining figure in school and everyone on the school grounds starts talking about a ghost. At that point, a mysterious transfer student called Yamazawa Norio suddenly arrives at the school.

An anime otaku named Sakamichi Onoda has just entered high school. In middle school, he did not have any friends with similar interests, but now he is hoping to find similar people at his new school's anime club.

Kohiruimaki Yuichi is a police officer who established the "Science Crime Countermeasures Office", a department that specializes in issues related to cutting-edge science and technology. He welcomes the genius scientist Mogami Yukiko as an advisor and she is in charge of investigating cases related to cutting-edge science. The crimes entrusted to the Science Crime Countermeasures Office are crimes that the legal system and police organization cannot keep up with. The two will unravel the science itself hidden behind the cases and not just the so-called forensic investigation. Hasebe Tsutomu is a detective who is not familiar with science but has a long experience in the field in the former Investigation Division.

Born in a family of delinquents, Nanba Tsuyoshi is expected to succeed as the strongest delinquent in school. Unbeknownst to his family however, he decides to enroll in the top high school in town to live as a normal high schooler. Can he maintain his double life as the strongest delinquent in town and as a normal high schooler?

Sato, a young woman from a modest family, marries Kenta, a young man from a well-to-do and respected family. She settles in the family's home, where she meets the father, Keiichi, a strict man, Mihoko, the unfriendly sister-in-law and Akito, the elder brother. Although not everyone sees the union of Kenta and Sato in a very good light, the father seems to have great plans for our heroine.