The series was originally announced to be a spin-off of the 2011 series Yes, Sir. Sorry, Sir! featuring the popular character "Miss Cool" portrayed by Chung. A costume fitting press conference was held on 21 November 2011 at Tseung Kwan O TVB City Studio One Common Room at 12:30PM.

Gossip magazine journalist Tong Leung-sing has unfortunately lost his left ear in a traffic accident. He gains mystical rat power after undergoing transplant surgery. Leung-sing keeps creating fake news just to benefit himself. He clashes with righteous policewoman Sung Hoi-yan, causing both of them to lose their jobs. With the support of her uncle Ming Kwan-ngai, Hoi-yan becomes a private investigator. Leung-sing is forced to help Hoi-yan with her investigation activities as Hoi-yan catches him using his mystical power to peep at goddess Ming Cheuk-kei. Gold digger Tong Mei-fun is cruelly harassed as rich clan heir Tsui Tsun-wai and she become foes. Mei-fun forgives Tsun-wai and offers to help him as Tsun-wai gets into a difficult situation. Leung-sing becomes increasingly arrogant as he uses to his mystical power to solve cases. Meanwhile, Hoi-yan shockingly finds out Kwan-ngai’s real character. Leung-sing faces the danger of exhausting his mystical power and becoming a rat as he helps Hoi-yan.

The characteristic of the Miscellaneous Enquiries (ME) unit is "miscellaneous"! Their investigations include nuisance, liquor licenses, non-criminal deaths and other uncategorized cases. ME Inspector Ben Wong enjoys the slow-paced life. When he meets the impatient and pregnant Mandy Wong, they naturally clash. Former undercover C Kwan has been lazy on the ME unit for many years. When he re-encounters his first love Jacqueline Wong, will it reignite his spirit? As the MEunit handles bizarre cases, there is tears among laughter.

Senior Forensic Chemist Jack 'Pro Sir' Po is the head of the Forensic Department and is skilled at analysing criminal psychology. He has a unique view on human nature and is familiar with the structure of various firearms. Pro Sir works closely with Senior Pathologist Mandy Chung in a wide range of fields including psychology, anthropology, criminology and forensic science.

Gordon Heung and Wai Sai-Lok have been long-time collaborators in the police force, frequently working with each other to solve drug trafficking cases in the city. During an operation, Sai-Lok discovers clues that point to Gordon being a corrupt cop in a collusion conspiracy with drug dealers. Suspicious about Gordon's true intentions, Sai-Lok launches a secret investigation on him.

The organization to which agent C9 Yue Siu-Kiu belongs is eradicated. Lonesome Siu-kiu encounters vegetable vendor Ko Tai-king. After getting married, she takes care of her father-in-law Ko Au, big sister-in-law Ko Ching-lai, younger brother-in-law Ko Tai-kiu and stepson Ko Hei-long, who collectively make up a dysfunctional family. She has become a proper housewife after five years. Siu-kiu’s former partner B3, who had escaped death, abruptly shows up to ask Siu-kiu to help find the culprit behind the demise of their organization. While Siu-kiu is keeping Tai-king in the dark, she simultaneously takes care of her family and carries out spying activities. But she does not perform well in either job. Black Hole, a terrorist group, goes after Siu-kiu as her identity is exposed. To protect her family, she bravely confronts Black Hole. Some shocking truth is also uncovered in the process, forcing Siu-kiu, Tai-king and their chums to engage the terrorists in a duel!

The story is set in the 1960s Hong Kong. The sincere Ko Tai Hei smuggles to Hong Kong, where his father's good friend Kam Lo Yik recommended him to join the police force. One time, he had an accident and got shot in the head. Pieces of the bullet went into his brain cells and oddly increased his IQ significantly. Since then, Hei turned into an intelligent detective capable of cracking down strange cases. However, his personality changed as well, turning him into a cold-hearted person who will do things by unscrupulous means.

MA FU, a retired employee of the HK Correctional Services Department, moved back to live with his son after retirement. MA FU treats and disciplines everyone in his family as if they were the offenders he works with in his job. His youngest son MA CHONG feels like he's in jail when he gets home, and his father is even often involved with his job as a paralegal. The father and son get into disputes daily and his elder brother MA KEUNG and his wife LO LAI SEUNG are often stuck in between and have to settle the disputes. The couple also holds the heavy responsibility of raising their kids. Three generations in the MA family all live together and encounter different situations, experiences and system of values.

Benjamin Yuen, an executive producer, has to deal with the pressure and demands from his boss, and the complaints of his subordinates. Every day, he is exhausted by his heavy workload until one day, he nearly dies. Luckily, paramedic Natalie Tong performs CPR to save his life. Later, Benjamin learns that to extend his life, he must kiss others to steal their time. He uses this to his advantage and sees big changes in his work, family and friendships. Unfortunately, because of him, Natalie suffered serious consequences. Aside from missing her wedding, her fiancé mysteriously goes missing. To help her regain her spirit, Benjamin takes over Yeung Chiu Hoi's coffee shop. He meets barista Hubert Wu and re-encounters his childhood friend Rebecca Zhu, a pole dancing teacher who has feelings for him. Benjamin, carrying the burden of extending his life, gradually develops feelings for Natalie, and fall into the anguish of loving each other but being unable to be together.

The sitcom is about office politics in a magazine company, as well as family and romantic relationships amongst the characters, with the majority of the cast from Best Selling Secrets.

My Date with a Vampire is a 1998 Hong Kong television series produced by ATV. The story is based on the future events of the plot of Vampire Expert, a similar two-season television drama aired on ATV in 1995 and 1996. It blends aspects of the jiangshi with those of western vampires, while injecting elements of Chinese mythology and modern horror legends. The series is a tribute to Lam Ching-ying, the lead actor of Vampire Expert and a prominent cast member in the Mr. Vampire franchise, who died of liver cancer in 1997. It was followed by My Date with a Vampire II and My Date with a Vampire III.

ICAC Investigators is a long running family of Hong Kong television miniseries about the work of Hong Kong's Independent Commission Against Corruption (ICAC). The series are public awareness films produced by Radio Television Hong Kong, an independent department of the government, with the full co-operation of the ICAC itself. Each series dramatises real cases of the Commission and serves both to educate the populace against corrupt practises and as a public relations tool for the ICAC.

Siu Wai-ming has been haunted by a dream of a woman wearing a cheongsam for many years. When he becomes an administrative manager for an old apartment building, he meets a tenant – air stewardess Alex Cheung – who looks exactly like the woman in his dream. As they get to know each other, the apartment building seems to come to life, performing the strange and fantastical lives of the tenants who live there.

Cheung Fei Fan, Ho Tit Nam and Ha Tin Hang are brothers who have been separated for many years. When the three were young, their lives scattered because of the 1997 Asian financial crisis. Many years later, they reunite and slowly they find out that there was a great conspiracy in their past.