Life for former United Nations investigator Gerry Lane and his family seems content. Suddenly, the world is plagued by a mysterious infection turning whole human populations into rampaging mindless zombies. After barely escaping the chaos, Lane is persuaded to go on a mission to investigate this disease. What follows is a perilous trek around the world where Lane must brave horrific dangers and long odds to find answers before human civilization falls.

Kate Stone is career-focused with a brash attitude that keeps relationships at an arm's length. When her estranged brother calls asking her to baby-sit her tween niece Maddie, Kate reluctantly agrees to help. But baby-sitting overnight unexpectedly turns into a week, and Kate's life spins into chaos. As Maddie reveals stories of being bullied and of wanting to run away and be a Juggalo, the two form a unique bond.

Brandon a socially awkward teen gets invited to a party by a potential love interest, everything goes south for him when his hooligan cousin screws over his chances; but they are forced to take matters into their own hands and make everything right.

When Grizz, Panda, and Ice Bear's love of food trucks and viral videos get out of hand, the brothers are now chased away from their home and embark on a trip to Canada, where they can live in peace.

A teenage girl with self-esteem issues finds confidence in the most unlikely way, by spending her summer battling vampires that prey on New Orleans' disenfranchised with the help of her best friend, the boy she's always pined for, and a peculiar rich girl.

Dexter Reed is down on his luck after another one of his inventions fails. Ed welcomes Dex back to Good Burger with open arms and gives him his old job back. With a new crew working at Good Burger, Dex devises a plan to get back on his feet but unfortunately puts the fate of Good Burger at risk once again.