A crime she committed in her youthful past sends Piper Chapman to a women's prison, where she trades her comfortable New York life for one of unexpected camaraderie and conflict in an eccentric group of fellow inmates.

In cases ripped from the headlines, police investigate serious and often deadly crimes, weighing the evidence and questioning the suspects until someone is taken into custody. The district attorney's office then builds a case to convict the perpetrator by proving the person guilty beyond a reasonable doubt. Working together, these expert teams navigate all sides of the complex criminal justice system to make New York a safer place.

After a night of partying with a female stranger, a man wakes up to find her stabbed to death and is charged with her murder.