A journalist duo go on a tour of serial killer murder sites with two companions, unaware that one of them is a serial killer himself.

In early-1970s Las Vegas, Sam "Ace" Rothstein gets tapped by his bosses to head the Tangiers Casino. At first, he's a great success in the job, but over the years, problems with his loose-cannon enforcer Nicky Santoro, his ex-hustler wife Ginger, her con-artist ex Lester Diamond and a handful of corrupt politicians put Sam in ever-increasing danger.

David, a naive graduate student, has volunteered to work as a 'buddy' for people dying of AIDS. Assigned to the intensely political Robert, a lifelong activist whose friends and family have abandoned him following his diagnosis, the two men, each with notably different world views, soon discover common bonds, as David's inner activist awakens and Robert's need for emotional release is fulfilled.

A newlywed couple move into the mansion of the bride's recently dead aunt. Soon strange things begin to happen when the various tenants and servants of the mansion don't want to leave and the bride and groom are in a deadly predicament.