Common people discover that they have super powers. Their lives intertwine as a devastating event must be prevented.

A Las Vegas team of forensic investigators are trained to solve criminal cases by scouring the crime scene, collecting irrefutable evidence and finding the missing pieces that solve the mystery.

A shallow model suddenly dies in an accident only to find her soul resurfacing in the body of a brilliant, plus-sized attorney.

Dr. Temperance Brennan and her colleagues at the Jeffersonian's Medico-Legal Lab assist Special Agent Seeley Booth with murder investigations when the remains are so badly decomposed, burned or destroyed that the standard identification methods are useless.

Raymond "Red" Reddington, one of the FBI's most wanted fugitives, surrenders in person at FBI Headquarters in Washington, D.C. He claims that he and the FBI have the same interests: bringing down dangerous criminals and terrorists. In the last two decades, he's made a list of criminals and terrorists that matter the most but the FBI cannot find because it does not know they exist. Reddington calls this "The Blacklist". Reddington will co-operate, but insists that he will speak only to Elizabeth Keen, a rookie FBI profiler.