Marisa and Dino are in one school and one class. Between them there are often quarrels over minor matters. Dino's friends are annoyed with Dino's always giving in, as well as Marisa's friends who like to give advice to Marisa, but Marisa doesn't care, Marisa is still mean to Dino.

A group of youngsters is on a mission to Ujung Sedo, to find their missing friends in a haunting jungle. Along the way, they met Samantha who's in a personal mission to the a mystical village. They went across the dark woods, a deafening fog, and a deadly cave where strange events followed them. Every twist is connected to Samantha who has a wicked curse to summon a she-devil called Kuntilanak. The old witch who lives in the village may be the only one who can stop the curse. But, that's not her plan at all.

Sam, or Samantha, has recently moved out from her old, haunted boarding house, escaping from followers of Mangkoedjiwo Sect who seek revenge over the death of Sri Sukmarahimi Mangkodjiwo. Her traumatic boyfriend, Agung, is looking for her. Sam sets herself apart in a new foster family to deal with her own dark side. The menace within her is raised stronger and stronger as she cannot stop herself from chanting the cursed chant to bring deadly punishments to people around her. Agung has to find her, and bring her back to pure conscience before the chant and her own dark side take over her life completely.

The most popular three reasons to enter the Faculty of Medicine are: income security, the prestigious diploma, or facilitating to get mate. Riva’s enter to the Faculty of Medicine is not for the three reasons above, but just goes along his friend named Evi, the girl he called best friend since high school. When co-ass or pre-med program begins, the proximity of the Riva and Vena, pretty co-ass and the girlo of the shareholder of the hospital, making the relationship between Riva and Evi cracked, because each reluctant to admit that they are more than just friends. As a result of a series of silly mistakes due to his own negligence, Riva blacklisted by the Professor. He began to doubt and question his choice to become a doctor. After the death of a patient, Riva aware of the real meaning of the vocation and the responsibility for his choice to become a doctor. Ahead of Evi’s departure, Riva realizes that what all this time they have is love.