John Stafford is unjustly arrested on the eve of his marriage for the murder of an old gentleman whose body was found in his guardian's library. The young man is taken to the penitentiary, but eludes his guards and escapes. His sweetheart engages a noted detective who finds a small Hindu image in the hand of the dead man.

Laura Bell runs away from her country home to the city, where she becomes a clerk in a department store. Her brother, Frank, follows her to New York, but is unable to place her. He becomes interested in a settlement house and obtains a position in social service work. Mary Ashton, daughter of the proprietor of the store where Laura works, is shocked to find that her father pays his clerks starvation wages.

Grinde is a junior partner of a pottery firm. An old chemist, Benjamin Lord, discovers a formula for glazing pottery that is designed to revolutionize the industry. The chemist's grandson, David, takes a sample of the new process to Grinde, who says he will give it consideration. He delegates his foreman, Mole, to steal the formula.

Oliver and Elizabeth wed. He is a famous lawyer, careless of his personal conduct, but has implicit faith in Elizabeth. She is a woman of strong mind, a magazine writer of repute, and believes he should guide himself by the same code that governs her. Two of their associates are profligates, Charles, an artist, and Catherine. Oliver trifles with Catherine and this so embitters Elizabeth, that she pretends to receive the attentions of Charles, although it is made clear that she has remained pure. Nevertheless, she purposely permits her husband to believe otherwise. He has considered her like Caesar's wife, but his faith is shattered. A child is born to her and the father doubts its parentage.

Inspired by his wife Lorna, shiftless William Gordon discovers a welding process worth millions and becomes president of a large corporation. Henry Blake, a friend of Gordon's from his indolent days, is forced to marry when his girl friend Mamie gives birth to a daughter, who is sent to live in a convent.

The son falls in love with his millionaire father's stenographer, against the parental wishes. To get rid of her influence over Wallace, Burton, Sr., discharges Madge. But the young man follows her and they are married. By so doing he separates himself from his father altogether.

The clerk has money to pay the last installment on his home, occupied by his old mother and himself, but meeting a fellow clerk and two girls is "forced" to treat in order to show that he really is no tightwad.

Sykes, an American engaged to a poor girl, goes to the Philippines as a teacher, and the girl stays behind to await their marriage. Sykes, after some time has passed, has succumbed to the tropic influences, and is living with a native girl, when one day he hears from the girl back home that she is coming to join him and that she will arrive at dawn next day. An aunt has died and left her a lot of money. Caring more for this coin that the girl, Sykes tries to get rid of the native girl, but she makes a row, and he in fear of losing his girl and her cash, poisons the native girl, who dies. He is about to get rid of the body when a young lieutenant of the U.S. Army shows up with his sergeant, inquiring the way to the trail of Indians, and becomes suspicious of Sykes' uneasiness and finds the dead girl.

Through the efforts of the Rev. John Drummond, who comes to a small western mining town with his little boy, all the saloons are closed. Jim Howe and his daughter, Nell, being unable to carry on a liquor business in the town, move to the mountains, where he runs an illicit still and continues to supply whiskey to the Indians. The sheriff gets on his trail and he is soon placed in the custody of the law. Nell, determining to avenge herself for the capture of her father, fires n shot into a party of hostile Indians, secreting herself in a bush as she does so. The Indians, seeing the soldiers coming, and thinking that they fired the shot, rush at them, but are defeated. This plan of revenge having failed, she makes her way to the minister's home, but is prevented from doing any harm to him by the maternal instinct which rises in her when she sees his little boy praying for his mother in heaven.

This shows the regeneration of a gang leader, who remains true to his first sweetheart after his change of fortune.