After an evening of drinking, six men find themselves in front of The God of the Joke. Distressed to find that people aren't laughing anymore, He gives the six friends a mission: to save the world with the Eleven Commandments of the Joke. The men enthusiastically take on their task. They undertake various tests aimed at pushing the limits of stupidity.

The story of four lifelong friends who met in the 2000s when they were presidents of the BDE of the Nantes Institute of Business. At the time, they were the "Bioman": the kings of partying, excess and "transmutation". 20 years later, they have mellowed out and lead well-ordered lives. Except... Once a year, when they get together for the WEB: the Bioman Weekend. There, they "transmute" hard as they like to say. In short: they drink and sing in a pathetic way.

The world is going bad, humans are no longer laughing, the situation is serious. the god of jokes has only one solution: michaël youn and his gang! their mission: to accomplish the 11 commandments of jokes in order to put people back on the right track of laughter by pushing back the limits of stupidity. waltzing in weightlessness at an altitude of 15,000 meters, flooding a house to turn it into a swimming pool, rollerblading under sleeping pills.

Alphonse Brown, who firmly believes he is the bastard son of James Brown, meets up with his best friend Scotch after Brown gets out of jail. On their way to Paris to begin careers as recording artists, the pair stumbles across a potent type of marijuana that was engineered by the Nazis. Their decision to begin selling the stuff leads to a variety of people chasing after them.