30-year-old single Mary Richards moves to Minneapolis to start a new life after a romantic break-up. There she reacquaints with Phyllis who rents her a room, and meets her upstairs neighbor and new best friend Rhoda. Mary unexpectedly lands a job as associate producer at the TV station WJM, where she works alongside her bristly boss, Lou; the comical newswriter, Murray; and the newscast's often-incompetent anchor, Ted.

Centres on the lives of three single girls living in bedsit-land in London SW3.