An aspiring doctor, Tupe gets falsely accused as being involved in the corrupt activities of his government official-father, affecting his relationship with Rita. Years after Tupe’s apparent disappearance, Rita finds a new love in Peterson, who credits her for becoming a changed man as he pursues political office. Complications arise, however, when Tupe and Rita cross paths again, triggering Peterson’s rage.

Daniel Villareal is trying to escape his tumultuous past. In a tragic event, he assumes the identity of Jacob del Rosario and starts life anew as a doting husband and family man to a homicide detective wife Iris Del Rosario. In a twist of events, his dark past as a suspected serial murderer catches up on him with his secrets unfolding. Detective Iris takes the lead on a case that will make his past catch up with the present, they will both stop at nothing to find out the truth and protect the life that they have built together even if it means going behind each other’s backs in order to do so.

Cynthia, a hopeful young woman filled with dreams and love for the people around her. Currently working as a nurse to sustain the needs of her poor but happy family, she has not given up on her greatest dream: to rebuild their family panaderia burnt to ashes in a fire incident years ago. In an unfortunate event, Cynthia is suddenly laid off from her job. This leads her to take on a new gig, a homecare nurse for a grumpy old lady. As she navigates a new job, challenges come along the way. Confused, Cynthia finds support from her family and a stranger named Franco.

Pinoy Big Brother, more popularly known by its abbreviated title PBB, is the Philippine version of Big Brother. The word Pinoy in the title is a colloquial term used to describe the Filipino people. The show first aired on August 21, 2005 on ABS-CBN, Studio 23, and its international channel, TFC in various countries worldwide. The uncut 24/7 version of the series can also be seen on the internet through paid-online streaming video subscription via TFCNow, and through cable network SkyCable. The show is currently hosted by Toni Gonzaga, Bianca Gonzalez, Robi Domingo, and John Prats. Other essential elements of the Big Brother franchise are present, such as weekly and daily challenges, the confessional room, and the voice known only as "Big Brother," sometimes referred to as "Kuya". Pinoy Big Brother uses their tagline "Teleserye ng Totoong Buhay" or the "Drama of Real Life".