Four egocentric friends run a neighborhood Irish pub in Philadelphia and try to find their way through the adult world of work and relationships. Unfortunately, their warped views and precarious judgments often lead them to trouble, creating a myriad of uncomfortable situations that usually only get worse before they get better.

Private detective Cassie Dewell partners with ex-cop Jenny Hoyt on a search for two sisters who have been kidnapped by a truck driver on a remote highway in Montana. When they discover that these are not the only girls who have disappeared in the area, they must race against the clock to stop the perpetrator before another woman is taken.